Cities and Towns in Middlesex County, Massachusetts

Founded in 1643, Middlesex County is one of 14 counties in the state of Massachusetts. Historically, Middlesex County was one of four original counties created in the Massachusetts Bay Colony. Government abolished in 1997. The city of Lowell, Cambridge is the county seat. With FIPS code of 17, Middlesex County has a population of 1,614,742 and area of 824 square miles (2,134 km²).

List of all cities in Middlesex County, MA alphabetically

City/Town	Postal Code	Area Code
Acton, MA	01718	978/351
	01719	978/351
	01720	978/351
Arlington, MA	02474	781/339
	02475	781/339
	02476	781/339
Arlington Heights, MA	02475	781/339
Ashby, MA	01431	978/351
Ashland, MA	01721	508/774
Auburndale, MA	02466	617/857
Ayer, MA	01432	978/351
	01434	978/351
Bank of America, MA	01815	781/339
Bedford, MA	01730	781/339
	01731	781/339
Belmont, MA	02478	781/339
	02479	781/339
Billerica, MA	01821	978/351
	01822	978/351
	01862	978/351
Boston College, MA	02467	617/857
Boxborough, MA	01719	978/351
Brookline, MA	02467	617/857
Burlington, MA	01803	781/339
	01805	781/339
Cambridge, MA	02138	617/857
	02139	617/857
	02140	617/857
	02141	617/857
	02142	617/857
	02238	617/857
Carlisle, MA	01741	978/351
Chelmsford, MA	01824	978/351
Cherry Brook, MA	02493	781/339
Chestnut Hill, MA	02467	617/857
Cochituate, MA	01778	508/774
Concord, MA	01742	978/351
Devens, MA	01432	978/351
	01434	978/351
Dracut, MA	01826	978/351
Dunstable, MA	01827	978/351
East Arlington, MA	02474	781/339
East Cambridge, MA	02141	617/857
East Pepperell, MA	01463	978/351
East Somerville, MA	02143	617/857
East Watertown, MA	02472	781/339
Everett, MA	02149	617/857
Field Premium Inc, MA	02477	617/857
Forge Village, MA	01886	978/351
Fort Devens, MA	01432	978/351
Framingham, MA	01701	508/774
	01702	508/774
	01703	508/774
	01704	508/774
	01705	508/774
Framingham Center, MA	01701	508/774
Framingham So, MA	01701	508/774
Groton, MA	01450	978/351
	01470	978/351
	01471	978/351
Hanscom AFB, MA	01731	781/339
Harvard Square, MA	02238	617/857
Hastings, MA	02493	781/339
Holliston, MA	01746	508/774
Hopkinton, MA	01748	508/774
Hudson, MA	01749	978/351
Inman Square, MA	02139	617/857
Kates Corner, MA	01824	978/351
Kendal Green, MA	02493	781/339
Kendall Square, MA	02142	617/857
Lahey Clinic Med Center, MA	01805	781/339
Lexington, MA	02420	781/339
	02421	781/339
Lincoln, MA	01773	781/339
Lincoln Center, MA	01773	781/339
Littleton, MA	01460	978/351
Lowell, MA	01850	978/351
	01851	978/351
	01852	978/351
	01853	978/351
	01854	978/351
Malden, MA	02148	781/339
Marlborough, MA	01752	508/774
Massachusetts District, MA	01889	978/351
Maynard, MA	01754	978/351
Medford, MA	02153	617/857
	02155	781/339
	02156	781/339
Mellon Financial Services, MA	01813	781/339
Melrose, MA	02176	781/339
Nabnasset, MA	01886	978/351
Natick, MA	01760	508/774
National Grid, MA	01807	781/339
New England Business, MA	01470	978/351
New England Business Svc Inc, MA	01471	978/351
New Town, MA	02456	617/857
Newton, MA	02456	617/857
	02458	617/857
	02459	617/857
	02460	617/857
	02461	617/857
	02462	617/857
	02464	617/857
	02465	617/857
	02466	617/857
	02467	617/857
	02468	617/857
	02495	617/857
Newton Center, MA	02459	617/857
Newton Highlands, MA	02461	617/857
Newton Lower Falls, MA	02462	617/857
Newton Upper Falls, MA	02464	617/857
Newtonville, MA	02458	617/857
	02460	617/857
	02462	617/857
Nonantum, MA	02495	617/857
North Billerica, MA	01862	978/351
North Cambridge, MA	02140	617/857
North Chelmsford, MA	01863	978/351
North Natick, MA	01760	508/774
North Reading, MA	01864	978/351
	01889	978/351
North Sudbury, MA	01776	978/351
North Waltham, MA	02451	781/339
	02452	781/339
	02455	617/857
Nutting Lake, MA	01865	978/351
Nuttings Lake, MA	01865	978/351
Pepperell, MA	01463	978/351
Pinehurst, MA	01866	781/339
Pingryville, MA	01460	978/351
Porter Square, MA	02140	617/857
Reading, MA	01867	781/339
Riverside, MA	02458	617/857
Saxonville, MA	01701	508/774
Sherborn, MA	01770	508/774
Shirley, MA	01464	978/351
Shirley Center, MA	01464	978/351
Silver Hill, MA	02493	781/339
Somerville, MA	02143	617/857
	02144	617/857
	02145	617/857
South Chelmsford, MA	01824	978/351
South Natick, MA	01760	508/774
South Waltham, MA	02453	781/339
Stoneham, MA	02180	781/339
Stony Brook, MA	02493	781/339
Stow, MA	01775	978/351
Sudbury, MA	01776	978/351
Tewksbury, MA	01876	978/351
Townsend, MA	01469	978/351
	01474	978/351
Tufts University, MA	02153	617/857
Tyngsboro, MA	01879	978/351
Village of Nagog Woods, MA	01718	978/351
Waban, MA	02468	617/857
Wakefield, MA	01880	781/339
Waltham, MA	02451	781/339
	02452	781/339
	02453	781/339
	02454	617/857
	02455	617/857
Watertown, MA	02471	617/857
	02472	781/339
	02477	617/857
Watertown Financial, MA	02471	617/857
Waverley, MA	02479	781/339
Wayland, MA	01778	508/774
West Acton, MA	01720	978/351
West Concord, MA	01742	978/351
West Groton, MA	01472	978/351
West Medford, MA	02155	781/339
	02156	781/339
West Newton, MA	02465	617/857
West Somerville, MA	02144	617/857
West Townsend, MA	01474	978/351
Westford, MA	01886	978/351
Weston, MA	02493	781/339
Wilmington, MA	01887	978/351
Winchester, MA	01890	781/339
Winter Hill, MA	02145	617/857
Woburn, MA	01801	781/339
	01807	781/339
	01813	781/339
	01815	781/339
	01888	781/339
Woodville, MA	01784	508/774

Major Cities and Towns in Middlesex County, Massachusetts

1. Cambridge

Area, Population, Zip Codes, Latitude and Longitude:

• Area: 7.13 square miles
• Population: 118,403 (2020 Census)
• Zip Codes: 02138, 02139, 02140, 02141, 02142
• Latitude: 42.3736° N
• Longitude: 71.1097° W

Location and History

Cambridge, located directly across the Charles River from Boston, is known as a center for education and innovation. Founded in 1630 and named after the University of Cambridge in England, the city became a significant intellectual hub during the 17th century. It is home to two world-renowned universities: Harvard University, founded in 1636 as the oldest higher education institution in the U.S., and the Massachusetts Institute of Technology (MIT), established in 1861. Cambridge has played a critical role in the American Revolution, and over the centuries, it evolved into a dynamic urban center known for its rich history, culture, and technology-driven economy.

Major Schools and Landmarks

In addition to Harvard and MIT, Cambridge has several public high schools, including Cambridge Rindge and Latin School, which is noted for its diverse student body. Notable landmarks include Harvard Yard, the historic center of Harvard University, and the Longfellow House, which was George Washington’s headquarters during the Siege of Boston. Kendall Square, near MIT, is known as “the most innovative square mile on the planet” due to its high concentration of tech companies and startups. Cambridge also boasts several cultural attractions, including the Harvard Art Museums and the American Repertory Theater. The city’s rich blend of academia, culture, and history makes it one of the most unique cities in the U.S.

2. Lowell

Area, Population, Zip Codes, Latitude and Longitude:

• Area: 14.5 square miles
• Population: 115,554 (2020 Census)
• Zip Codes: 01850, 01851, 01852, 01854
• Latitude: 42.6334° N
• Longitude: 71.3162° W

Location and History

Lowell, located in the northern part of Middlesex County, was founded in the early 19th century as America’s first planned industrial city. Known as the birthplace of the American Industrial Revolution, Lowell became a major center for textile manufacturing, attracting workers from across the country and around the world. The city was named after Francis Cabot Lowell, a key figure in industrializing the textile industry. Lowell’s canals, mills, and factories fueled its growth, and today, the Lowell National Historical Park preserves the city’s industrial heritage. Despite periods of economic decline, Lowell has experienced revitalization in recent decades.

Major Schools and Landmarks

Lowell is home to the University of Massachusetts Lowell (UMass Lowell), a major public research university. Lowell High School, one of the oldest public high schools in the U.S., serves the city’s students. Significant landmarks include the Lowell National Historical Park, which features restored mills, canals, and museums that tell the story of the Industrial Revolution. The city also hosts the annual Lowell Folk Festival, one of the largest free folk festivals in the country. Other key attractions include the Boott Cotton Mills Museum and the Whistler House Museum of Art, dedicated to the artist James McNeill Whistler, who was born in Lowell.

3. Somerville

Area, Population, Zip Codes, Latitude and Longitude:

• Area: 4.12 square miles
• Population: 81,045 (2020 Census)
• Zip Codes: 02143, 02144, 02145
• Latitude: 42.3876° N
• Longitude: 71.0995° W

Location and History

Somerville is located just north of Cambridge and was originally part of Charlestown before becoming an independent town in 1842. Historically a center for brick manufacturing and other industries, Somerville experienced rapid development during the 19th century due to its proximity to Boston. The city became known for its working-class roots and ethnic diversity, particularly with the influx of Irish and Italian immigrants. In recent decades, Somerville has undergone significant gentrification and is now a vibrant urban area with a thriving arts scene, tech startups, and popular residential neighborhoods like Davis Square.

Major Schools and Landmarks

Somerville High School serves the city’s students, along with several elementary and middle schools. The city is home to Tufts University, which straddles the border between Somerville and Medford. Key landmarks include Assembly Row, a modern development featuring shopping, dining, and entertainment along the Mystic River, and the historic Prospect Hill Monument, where George Washington’s army raised the first American flag during the Revolutionary War. Davis Square is a cultural hub, offering theaters, music venues, and public art. The Somerville Open Studios event showcases the city’s thriving artist community, while the Fluff Festival celebrates the invention of Marshmallow Fluff, which originated in Somerville.

4. Newton

Area, Population, Zip Codes, Latitude and Longitude:

• Area: 18.19 square miles
• Population: 88,923 (2020 Census)
• Zip Codes: 02458, 02459, 02460, 02461, 02462, 02464, 02465, 02466, 02467, 02468
• Latitude: 42.3370° N
• Longitude: 71.2092° W

Location and History

Newton is a suburban city located just west of Boston, known for its historic villages and affluent neighborhoods. Settled in 1630 and incorporated as a town in 1688, Newton developed as a residential community during the 19th century, with the construction of railroads and trolleys linking it to Boston. Newton is known for its high quality of life, excellent schools, and spacious homes. It is often referred to as “The Garden City” because of its green spaces and tree-lined streets. Newton consists of 13 distinct villages, each with its own character, including Newton Centre, Newtonville, and Chestnut Hill.

Major Schools and Landmarks

Newton is served by Newton North High School and Newton South High School, both of which are highly regarded. Boston College, a prestigious Jesuit university, is located in Chestnut Hill, on the Newton-Brighton line. Landmarks in Newton include the historic Jackson Homestead, now the Newton History Museum, and Crystal Lake, a popular spot for swimming and picnicking. The Chestnut Hill Reservoir and the scenic Charles River offer recreational opportunities. Newton is also home to the Boston Marathon’s famous “Heartbreak Hill,” a challenging part of the race route. The annual Newton Arts Festival highlights the city’s vibrant cultural scene.

5. Waltham

Area, Population, Zip Codes, Latitude and Longitude:

• Area: 13.61 square miles
• Population: 65,218 (2020 Census)
• Zip Codes: 02451, 02452, 02453, 02454
• Latitude: 42.3765° N
• Longitude: 71.2356° W

Location and History

Waltham, located along the Charles River, is known as the “Watch City” due to its role as a major center for watchmaking in the 19th century. Waltham became an early industrial hub, with the Waltham Watch Company, the first company to mass-produce watches using an assembly line, being a key player. The city’s location along the Charles River provided power for the factories that fueled its growth. Waltham is also home to two prestigious universities, Brandeis University and Bentley University, which contribute to the city’s academic and cultural vitality. In recent years, Waltham has developed into a center for high-tech and biotech companies.

Major Schools and Landmarks

Waltham High School serves the city’s students, and higher education institutions include Brandeis University and Bentley University. Major landmarks include the Charles River Museum of Industry and Innovation, which tells the story of Waltham’s industrial past, and the Gore Place, a historic estate and museum. The Lyman Estate, a grand Federal-style mansion, is another significant historical site. Moody Street, known as “Restaurant Row,” is a popular dining and entertainment destination, offering a variety of international cuisines. Waltham also hosts the annual Watch City Steampunk Festival, which celebrates the city’s industrial heritage with a modern twist.

6. Framingham

Area, Population, Zip Codes, Latitude and Longitude:

• Area: 25.1 square miles
• Population: 72,362 (2020 Census)
• Zip Codes: 01701, 01702, 01703, 01704, 01705
• Latitude: 42.2793° N
• Longitude: 71.4162° W

Location and History

Framingham, located about 20 miles west of Boston, is one of the largest towns in Massachusetts and was recently incorporated as a city in 2018. Settled in 1650, Framingham grew as an agricultural community and later became a center for manufacturing during the Industrial Revolution. The construction of railroads in the 19th century spurred further growth, turning Framingham into a transportation hub. In the 20th century, Framingham became known for the Framingham Heart Study, a landmark medical study that has contributed to our understanding of cardiovascular disease. Today, Framingham is a diverse city with a mix of residential, commercial, and industrial areas.

Major Schools and Landmarks

Framingham High School is the main public high school, and Framingham State University is a prominent institution for higher education in the city. Major landmarks include the Framingham Historical Society and Museum, which preserves the city’s colonial history, and the Garden in the Woods, a botanical garden that showcases New England’s native plants. The city is also home to the Framingham Centre Common Historic District, featuring historic homes and churches. Cushing Memorial Park and Callahan State Park offer outdoor recreation opportunities. Framingham’s proximity to Boston and its rich history make it a vibrant and growing community.