Founded in 1849, Butler County is one of 114 counties in the state of Missouri. Historically, Butler County was formed from Wayne County. The city of Poplar Bluff is the county seat. With FIPS code of 23, Butler County has a population of 42,101 and area of 698 square miles (1,808 km2).
List of all cities in Butler County, MO alphabetically
| City/Town | Postal Code | Area Code |
| Broseley, MO | 63932 | 573 |
| Fagus, MO | 63938 | 573 |
| Fisk, MO | 63940 | 573 |
| Harviell, MO | 63945 | 573 |
| Neelyville, MO | 63954 | 573 |
| Poplar Bluff, MO | 63901 | 573 |
| 63902 | 573 | |
| Qulin, MO | 63938 | 573 |
| 63961 | 573 | |
| Rombauer, MO | 63901 | 573 |
| 63962 | 573 |