Founded in 1818, Wayne County is one of 114 counties in the state of Missouri. Historically, Wayne County was formed from Cape Girardeau and Lawrence counties. The city of Greenville is the county seat. With FIPS code of 223, Wayne County has a population of 10,914 and area of 761 square miles (1,971 km2).
List of all cities in Wayne County, MO alphabetically
| City/Town | Postal Code | Area Code |
| Cascade, MO | 63632 | 573 |
| Clubb, MO | 63934 | 573 |
| Coldwater, MO | 63964 | 573 |
| Greenville, MO | 63944 | 573 |
| Hiram, MO | 63944 | 573 |
| Lodi, MO | 63950 | 573 |
| Lowndes, MO | 63951 | 573 |
| Mc Gee, MO | 63763 | 573 |
| Mill Spring, MO | 63952 | 573 |
| Patterson, MO | 63956 | 573 |
| Piedmont, MO | 63957 | 573 |
| Shook, MO | 63963 | 573 |
| Silva, MO | 63934 | 573 |
| 63964 | 573 | |
| Wappapello, MO | 63966 | 573 |
| Williamsville, MO | 63967 | 573 |