Cities and Towns in Wayne County, Missouri

Founded in 1818, Wayne County is one of 114 counties in the state of Missouri. Historically, Wayne County was formed from Cape Girardeau and Lawrence counties. The city of Greenville is the county seat. With FIPS code of 223, Wayne County has a population of 10,914 and area of 761 square miles (1,971 km²).

List of all cities in Wayne County, MO alphabetically

City/Town	Postal Code	Area Code
Cascade, MO	63632	573
Clubb, MO	63934	573
Coldwater, MO	63964	573
Greenville, MO	63944	573
Hiram, MO	63944	573
Lodi, MO	63950	573
Lowndes, MO	63951	573
Mc Gee, MO	63763	573
Mill Spring, MO	63952	573
Patterson, MO	63956	573
Piedmont, MO	63957	573
Shook, MO	63963	573
Silva, MO	63934	573
	63964	573
Wappapello, MO	63966	573
Williamsville, MO	63967	573

Major Cities and Towns in Wayne County, Missouri

Piedmont

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 3.03 sq mi
• Population: 1,936 (2020 Census)
• Zip Codes: 63957
• Latitude: 37.3886° N
• Longitude: 90.6184° W

Location and History

Piedmont is the largest city and the county seat of Wayne County, located in the southeastern part of Missouri, along the banks of the Black River. Established in the mid-1800s, the city was originally a trading post and small settlement that grew around the river, which provided vital transportation and trade routes for early settlers. Piedmont was named after the Piedmont region of Italy, reflecting the aspirations of its founders. The town expanded rapidly with the arrival of the railroad in the late 19th century, which helped connect the city to larger commercial centers. Over the years, Piedmont developed as a hub for local agriculture, particularly cattle farming and timber, as well as small industry. In recent decades, the city has embraced its role as a center for tourism, thanks to its proximity to the beautiful Mark Twain National Forest and the Ozarks.

Major Schools and Landmarks

Piedmont is served by the Clearwater R-I School District, which includes Clearwater High School. The district is known for its strong academic programs and community involvement. Notable landmarks in Piedmont include the Piedmont Community Park, which features recreational facilities like walking trails, sports fields, and picnic areas. The Black River, a key feature of the region, is popular for fishing, kayaking, and canoeing. Visitors also flock to the nearby Mark Twain National Forest, which offers hiking, camping, and wildlife viewing. The Wayne County Historical Society Museum, located in the heart of Piedmont, preserves the history of the town and the surrounding area, offering educational exhibits on local culture, the Civil War, and the area’s development.

Greenville

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 0.93 sq mi
• Population: 501 (2020 Census)
• Zip Codes: 63944
• Latitude: 37.3122° N
• Longitude: 90.6340° W

Location and History

Greenville is a small town located in the northeastern part of Wayne County, along the St. Francis River. Founded in the early 1800s, Greenville was initially a center for trade and agriculture due to its location on the river. The town’s early economy was primarily based on farming and timber, but it also became known for its role in river transportation, with steamboats navigating the St. Francis River during the 19th century. The town grew modestly during the 20th century, but its small size and rural location kept its growth steady rather than rapid. Greenville’s history includes a notable event during the Civil War when Confederate forces passed through the area. Today, the town maintains a quiet, rural character, with many of its residents engaged in farming and outdoor activities.

Major Schools and Landmarks

Greenville is part of the Greenville R-II School District, which includes Greenville High School. The district offers a strong academic curriculum and emphasizes extracurricular activities. Key landmarks in Greenville include the St. Francis River, which is popular for fishing, boating, and scenic views. The town is near the Sam A. Baker State Park, a major recreational destination that provides hiking, camping, fishing, and picnic areas. Sam A. Baker State Park also features the beautiful St. Francis River, providing opportunities for canoeing and kayaking. Additionally, Greenville hosts local festivals and events that celebrate its heritage and attract visitors from across the region. Though small, Greenville is known for its welcoming community and its access to outdoor recreation.

Williamsville

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 0.44 sq mi
• Population: 157 (2020 Census)
• Zip Codes: 63967
• Latitude: 37.2211° N
• Longitude: 90.4212° W

Location and History

Williamsville is a tiny town located in the southern part of Wayne County, nestled in the Ozark foothills. It was established in the early 1800s and named after the Williams family, some of the earliest settlers in the area. The town has always been a small agricultural community, with its economy historically tied to farming, especially cattle ranching, and timber. Over the years, Williamsville has maintained a rural, quiet atmosphere, with only modest growth. Like many small towns in the region, Williamsville’s economy has remained largely based on natural resources and agriculture. The town saw a brief increase in population in the mid-1900s when local logging activities were at their peak. Today, Williamsville’s population is small but steady, with many residents working in nearby towns or in agriculture.

Major Schools and Landmarks

Williamsville is served by the Williamsville R-III School District, which includes a small primary school offering education for younger children in the area. The town itself is quite small, but nearby landmarks include the St. Francis River, which runs close by, providing ample opportunities for outdoor activities such as fishing, hiking, and camping. Williamsville is within easy reach of the Mark Twain National Forest, making it a great spot for those interested in exploring the natural beauty of the Ozarks. The town also celebrates its rural heritage with community events, including local fairs and outdoor gatherings. Despite its small size, Williamsville offers a peaceful, scenic environment for those seeking a quieter lifestyle.

Richwoods

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 0.39 sq mi
• Population: 155 (2020 Census)
• Zip Codes: 63662
• Latitude: 37.4986° N
• Longitude: 90.4736° W

Location and History

Richwoods is a small rural town located in the southern part of Wayne County, surrounded by farmland and forests. The town was originally settled in the 1800s, with many of its early residents coming from the surrounding Appalachian region, bringing their traditions and rural way of life with them. Richwoods developed slowly, with most of its early growth focused around agriculture, particularly the cultivation of tobacco and corn. Over the years, the town’s population has remained small, with its residents largely working in farming or commuting to larger nearby towns for employment. Richwoods holds a special place in the local history of Wayne County, as it was once a vital stop along local trade routes and has been the site of numerous historical events, including early settlements and Civil War activity.

Major Schools and Landmarks

Richwoods is part of the Richwoods R-VII School District, which includes a primary school offering educational opportunities for the town’s youth. Key landmarks in Richwoods include the nearby Ozark National Scenic Riverways, where residents and visitors enjoy fishing, canoeing, and hiking in the picturesque natural landscape. Richwoods is also known for its proximity to the Mark Twain National Forest, providing a range of outdoor activities, including camping, hiking, and wildlife watching. While Richwoods remains small, its surrounding natural beauty and peaceful, rural lifestyle offer a charming and quiet escape from the hustle and bustle of nearby cities. Local festivals and events also help maintain a strong sense of community.