Founded in 1809, Wayne County is one of 82 counties in the state of Mississippi. Historically, Wayne County was formed from Washington County (AL). The city of Waynesboro is the county seat. With FIPS code of 153, Wayne County has a population of 19,709 and area of 810 square miles (2,098 km2).
List of all cities in Wayne County, MS alphabetically
| City/Town | Postal Code | Area Code |
| Buckatunna, MS | 39322 | 601/769 |
| Clara, MS | 39324 | 601/769 |
| Waynesboro, MS | 39367 | 662 |
| Wboro, MS | 39367 | 662 |