Cities and Towns in Saint Clair County, Missouri

Founded in 1841, Saint Clair County is one of 114 counties in the state of Missouri. Historically, Saint Clair County was formed from Rives (now Henry) County. The city of Osceola is the county seat. With FIPS code of 185, Saint Clair County has a population of 9,376 and area of 677 square miles (1,753 km²).

List of all cities in Saint Clair County, MO alphabetically

City/Town	Postal Code	Area Code
Appleton City, MO	64724	660
Collins, MO	64738	417
Damascus, MO	64776	417
Lowry City, MO	64763	417
Osceola, MO	64776	417
Roscoe, MO	64781	417
Vista, MO	64776	417

Major Cities and Towns in Saint Clair County, Missouri

Osceola

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 1.06 sq mi
• Population: 900+ (2020 Census)
• Zip Codes: 64776
• Latitude: 38.1105° N
• Longitude: 93.6700° W

Location and History

Osceola is the county seat of St. Clair County, located in the southwestern part of Missouri, near the Osage River. The town was established in 1837 and was originally named for the prominent Seminole leader, Osceola. Osceola’s history is deeply tied to the westward expansion of the United States and the Native American tribes in the region. The town developed as a trading post and later became a hub for local agriculture, particularly wheat farming, as settlers moved into the area. Osceola was also an important point on the stagecoach route connecting Missouri to Kansas, making it a key stop for travelers and traders. During the Civil War, the town played a strategic role due to its location on the Osage River, and it was briefly occupied by both Union and Confederate forces. In the late 19th and early 20th centuries, Osceola became a quiet rural community, though it continued to be a central location for the surrounding agricultural region. Today, Osceola retains its historic charm, with many original buildings preserved from its early days.

Major Schools and Landmarks

Osceola is served by the Osceola R-1 School District, which includes Osceola High School, Osceola Middle School, and several elementary schools. The district is known for its strong academic programs and a commitment to offering students opportunities for extracurricular involvement in sports, arts, and community service. Key landmarks in Osceola include the St. Clair County Courthouse, a historic building that serves as the center of county government, and the Osceola Public Library, which provides educational resources and hosts community events. Another notable landmark is the Osceola City Park, which features walking trails, picnic areas, and a large lake for fishing and recreation. The nearby Truman Lake offers outdoor activities such as boating, fishing, and camping, drawing visitors to the area for its scenic views and wildlife. Osceola also boasts several preserved historic homes and buildings, adding to the town’s charm as a destination for history lovers and tourists. Overall, Osceola is a community where residents value history, education, and outdoor recreation.

Appleton City

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 1.10 sq mi
• Population: 1,200+ (2020 Census)
• Zip Codes: 64724
• Latitude: 38.2928° N
• Longitude: 93.4104° W

Location and History

Appleton City, located in the central part of St. Clair County, was founded in 1871 and named for the abundance of apple orchards in the area at the time. It grew rapidly as a railroad town, serving as a hub for the region’s agricultural products, particularly apples, which were cultivated in large quantities during the late 19th and early 20th centuries. Like many towns in Missouri, Appleton City prospered from its position along a major transportation route—the railroad—and its connection to farming and local industry. In the 20th century, as the apple industry declined, the town shifted its focus to other forms of agriculture, including livestock and grain farming. Appleton City remains a small but active rural community, with agriculture still serving as the backbone of the local economy. The city’s location along U.S. Route 49 makes it a convenient stop for travelers, but it has preserved its small-town atmosphere and historical charm.

Major Schools and Landmarks

Appleton City is served by the Appleton City R-II School District, which includes Appleton City High School, known for its athletics, particularly in basketball and football, and its strong academic programs. The district also offers a variety of extracurricular activities, such as FFA (Future Farmers of America), 4-H, and arts programs. In terms of landmarks, Appleton City is home to several historically significant buildings, including the Appleton City Museum, which highlights the town’s history and the region’s agricultural heritage. The town’s downtown area is characterized by small, locally-owned shops and restaurants, preserving the feel of a classic rural town. Appleton City Park offers walking trails, sports fields, and a playground, providing residents with a venue for outdoor recreation. The surrounding countryside is dotted with farms, and the area is well-known for its beautiful rural landscapes, making it a prime location for outdoor activities like hunting, hiking, and photography. Additionally, Appleton City is a popular stop for those traveling through the region due to its quaint atmosphere and access to nearby lakes and parks.

Lowry City

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 0.83 sq mi
• Population: 650+ (2020 Census)
• Zip Codes: 64763
• Latitude: 38.1004° N
• Longitude: 93.6791° W

Location and History

Lowry City, located in the southern part of St. Clair County, was founded in 1883. The town was named after the Lowry family, who were early settlers in the area and played a significant role in its development. Like many small towns in Missouri, Lowry City grew in part due to its location along the railroad, which facilitated the transportation of agricultural products. Early industries in the town were centered around farming, with the fertile land producing a variety of crops, including corn, soybeans, and wheat. In the 20th century, Lowry City remained a rural community, with farming continuing to be the dominant economic activity. The town’s population has remained small, and it has retained its charm as a quiet, tight-knit community. In recent years, the town has seen some growth due to its proximity to larger cities like Clinton, which has made Lowry City an attractive place for those seeking a quieter, rural lifestyle. Today, Lowry City is primarily residential and agricultural but offers a welcoming atmosphere for those who enjoy small-town living.

Major Schools and Landmarks

Lowry City is served by the Lakeland R-III School District, which includes Lakeland High School. The district is known for its small class sizes, which provide a more individualized education experience. Lakeland High School offers a strong curriculum, along with sports teams, clubs, and a focus on community service. The town itself has a few notable landmarks, including the Lowry City Historical Society, which helps preserve the town’s history through exhibits and events. Lowry City is also home to the Lowry City City Park, which features a playground, sports fields, and picnic areas. The park is a popular spot for local gatherings and outdoor activities. One of the town’s major landmarks is the nearby Truman Lake, which offers a variety of outdoor recreation options, including boating, fishing, and camping. Lowry City is known for its scenic rural landscapes, and the area is popular for hunting and fishing, drawing visitors to the region for outdoor activities year-round. The town may be small, but it offers a peaceful and welcoming environment for residents and visitors alike.

Roscoe

Area, Population, Zip Codes, Latitude, and Longitude

• Area: 0.37 sq mi
• Population: 200+ (2020 Census)
• Zip Codes: 64781
• Latitude: 38.0470° N
• Longitude: 93.6452° W

Location and History

Roscoe is a small unincorporated community in the northeastern part of St. Clair County. Originally settled in the mid-19th century, Roscoe developed as a rural farming town and remained primarily agricultural throughout its history. The community was named after Roscoe L. Porter, one of its early settlers, who established the town as a trading hub for the surrounding farming communities. While the town has always remained small, it played a key role in the region’s agricultural economy, particularly as a gathering place for farmers to transport their goods. Over the years, Roscoe’s population has remained relatively stable, with the town serving as a quiet and peaceful location for those looking to escape the bustle of larger cities. Today, it is largely residential with a strong agricultural influence in the surrounding area.

Major Schools and Landmarks

Roscoe is served by the Lowry City and other surrounding school districts, with children typically attending school in nearby towns. The town itself does not have many large institutions but is part of the local agricultural and historical scene. The most notable landmarks in Roscoe include the small Roscoe Methodist Church, which serves as a community gathering place, and the nearby farming operations that define much of the region. The community also takes pride in its rural lifestyle and is close to Truman Lake, which provides residents with access to outdoor recreation. Fishing, boating, and camping are popular activities in the area, making Roscoe an appealing place for those who enjoy the outdoors. The quiet atmosphere and rural charm make Roscoe a peaceful place for those seeking to live close to nature.