Founded on Dec 7, 1836, Louisa County is one of 99 counties in the state of Iowa. Historically, Louisa County was formed from Des Moines County. The city of Wapello is the county seat. With FIPS code of 115, Louisa County has a population of 10,749 and area of 402 square miles (1,041 km2).
List of all cities in Louisa County, IA alphabetically
| City/Town | Postal Code | Area Code |
| Cairo, IA | 52738 | 319 |
| Columbus City, IA | 52737 | 319 |
| Columbus Junction, IA | 52738 | 319 |
| Cotter, IA | 52738 | 319 |
| Cranston, IA | 52754 | 319 |
| Elrick, IA | 52653 | 319 |
| Fredonia, IA | 52738 | 319 |
| Gladwin, IA | 52738 | 319 |
| Grandview, IA | 52752 | 319 |
| Huron, IA | 52646 | 319 |
| Letts, IA | 52754 | 319 |
| Morning Sun, IA | 52640 | 319 |
| Oakville, IA | 52646 | 319 |
| Toolesboro, IA | 52653 | 319 |
| Wapello, IA | 52653 | 319 |