Founded in 1816, Jackson County is one of 102 counties in the state of Illinois. Historically, Jackson County was formed from Randolph County and Johnson County. The city of Murphysboro is the county seat. With FIPS code of 77, Jackson County has a population of 52,565 and area of 584 square miles (1,513 km2).
List of all cities in Jackson County, IL alphabetically
| City/Town | Postal Code | Area Code |
| Ava, IL | 62907 | 618/730 |
| Boskydell, IL | 62901 | 618/730 |
| Briarwood Trace, IL | 62901 | 618/730 |
| Brush Hill, IL | 62901 | 618/730 |
| Bush, IL | 62924 | 618/730 |
| Campbell Hill, IL | 62916 | 618/730 |
| Carbondale, IL | 62901 | 618/730 |
| 62902 | 618/730 | |
| 62903 | 618/730 | |
| CDALE, IL | 62901 | 618/730 |
| Chamnesstown, IL | 62932 | 618/730 |
| Crab Orchard Estates, IL | 62901 | 618/730 |
| De Soto, IL | 62924 | 618/730 |
| Degognia, IL | 62950 | 618/730 |
| Dowell, IL | 62927 | 618/730 |
| Elkville, IL | 62932 | 618/730 |
| Etherton, IL | 62966 | 618/730 |
| Fountain Bluff, IL | 62950 | 618/730 |
| Gorham, IL | 62940 | 618/730 |
| Grand Tower, IL | 62942 | 618/730 |
| Grimsby, IL | 62940 | 618/730 |
| Hallidayboro, IL | 62932 | 618/730 |
| Howardton, IL | 62942 | 618/730 |
| Jacob, IL | 62950 | 618/730 |
| Kinkaid, IL | 62907 | 618/730 |
| Lake Tacoma, IL | 62901 | 618/730 |
| Lakewood Park, IL | 62901 | 618/730 |
| Levan, IL | 62966 | 618/730 |
| Makanda, IL | 62958 | 618/730 |
| Mboro, IL | 62966 | 618/730 |
| Midland Hills, IL | 62958 | 618/730 |
| Mount Carbon, IL | 62966 | 618/730 |
| Murphysboro, IL | 62966 | 618/730 |
| Neunert, IL | 62950 | 618/730 |
| Oraville, IL | 62971 | 618/730 |
| Pomona, IL | 62975 | 618/730 |
| Raddle, IL | 62950 | 618/730 |
| Red Town, IL | 62942 | 618/730 |
| Sand Ridge, IL | 62940 | 618/730 |
| Shiloh Hill, IL | 62916 | 618/730 |
| Somerset, IL | 62966 | 618/730 |
| Triple Lake Heights, IL | 62901 | 618/730 |
| Vergennes, IL | 62994 | 618/730 |