Founded in May 1, 1803, Scioto County is one of 88 counties in the state of Ohio. Historically, Scioto County was formed from Adams County. The city of Portsmouth is the county seat. With FIPS code of 145, Scioto County has a population of 73,346 and area of 612.27 square miles (1,586 km2).
List of all cities in Scioto County, OH alphabetically
| City/Town | Postal Code | Area Code |
| Franklin Furnace, OH | 45629 | 740 |
| Friendship, OH | 45630 | 740 |
| Haverhill, OH | 45636 | 740 |
| Lucasville, OH | 45648 | 740 |
| Lucasville, OH | 45699 | 740 |
| McDermott, OH | 45652 | 740 |
| Minford, OH | 45653 | 740 |
| New Boston, OH | 45662 | 740 |
| Otway, OH | 45657 | 740 |
| Portsmouth, OH | 45662 | 740 |
| 45663 | 740 | |
| Rarden, OH | 45671 | 740 |
| Scioto Furnace, OH | 45677 | 740 |
| Sciotoville, OH | 45662 | 740 |
| So Oh Correctional Facility, OH | 45699 | 740 |
| South Webster, OH | 45682 | 740 |
| Stream Side, OH | 45629 | 740 |
| West Portsmouth, OH | 45663 | 740 |
| Wheelersburg, OH | 45694 | 740 |