Founded in 1798, Lancaster County is one of 46 counties in the state of South Carolina. Historically, Lancaster County was formed from Camden District. The city of Lancaster is the county seat. With FIPS code of 57, Lancaster County has a population of 100,336 and area of 555 square miles (1,437 km2).
List of all cities in Lancaster County, SC alphabetically
| City/Town | Postal Code | Area Code |
| Abney, SC | 29067 | 803 |
| Fort Mill, SC | 29707 | 803 |
| Heath Springs, SC | 29058 | 803 |
| Indian Land, SC | 29707 | 803 |
| Kershaw, SC | 29067 | 803 |
| Lancaster, SC | 29720 | 803 |
| 29721 | 803 | |
| 29722 | 803 | |
| Pleasant Hill, SC | 29058 | 803 |
| Spring Mills, SC | 29067 | 803 |
| Stoneboro, SC | 29058 | 803 |
| Taxahaw, SC | 29067 | 803 |
| Van Wyck, SC | 29744 | 803 |
| White Bluff, SC | 29067 | 803 |