Founded in 1833, Tallahatchie County is one of 82 counties in the state of Mississippi. Historically, Tallahatchie County was formed from Washington and Yazoo Counties. The city of Charleston, Sumner is the county seat. With FIPS code of 135, Tallahatchie County has a population of 12,366 and area of 644 square miles (1,668 km2).
List of all cities in Tallahatchie County, MS alphabetically
| City/Town | Postal Code | Area Code |
| Albin, MS | 38966 | 662 |
| Brazil, MS | 38963 | 662 |
| Cascilla, MS | 38920 | 662 |
| Charlestn, MS | 38958 | 662 |
| Charleston, MS | 38921 | 662 |
| 38958 | 662 | |
| Cowart, MS | 38921 | 662 |
| Effie, MS | 38921 | 662 |
| Enid, MS | 38927 | 662 |
| Glendora, MS | 38928 | 662 |
| Greenwood-Leflore Airport, MS | 38920 | 662 |
| Leverett, MS | 38920 | 662 |
| Macel, MS | 38950 | 662 |
| Paul, MS | 38920 | 662 |
| Paynes, MS | 38920 | 662 |
| Philipp, MS | 38950 | 662 |
| Rosebloom, MS | 38920 | 662 |
| Sharkey, MS | 38921 | 662 |
| Sumner, MS | 38957 | 662 |
| Swan Lake, MS | 38958 | 662 |
| Teasdale, MS | 38927 | 662 |
| Tippo, MS | 38962 | 662 |
| Tutwiler, MS | 38963 | 662 |
| Webb, MS | 38966 | 662 |
| Whitehead, MS | 38928 | 662 |