Founded in 1876, Gaines County is one of 254 counties in the state of Texas. Historically, Gaines County was formed from Bexar County. The city of Seminole is the county seat. With FIPS code of 165, Gaines County has a population of 21,895 and area of 1,502 square miles (3,890 km2).
List of all cities in Gaines County, TX alphabetically
| City/Town | Postal Code | Area Code |
| Loop, TX | 79342 | 806 |
| Seagraves, TX | 79359 | 806 |
| Seminole, TX | 79360 | 432 |