Founded in 1848, Medina County is one of 254 counties in the state of Texas. Historically, Medina County was formed from Bexar County. The city of Hondo is the county seat. With FIPS code of 325, Medina County has a population of 51,981 and area of 1,328 square miles (3,440 km2).
List of all cities in Medina County, TX alphabetically
| City/Town | Postal Code | Area Code |
| Castroville, TX | 78009 | 830 |
| 78056 | 830 | |
| D Hanis, TX | 78850 | 830 |
| Devine, TX | 78016 | 830 |
| Dunlay, TX | 78861 | 830 |
| Hondo, TX | 78861 | 830 |
| La Coste, TX | 78039 | 830 |
| Mico, TX | 78056 | 830 |
| Natalia, TX | 78059 | 830 |
| Rio Medina, TX | 78066 | 830 |
| Yancey, TX | 78886 | 830 |